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Discover - Google+Schizophrenia affects whole- brain connectivity."We can definitively say for the first time that schizophrenia is a disorder where white matter wiring is frayed throughout the brain."- -- -- -- -- -- -- -- -- -- -- -Schizophrenia can disrupt the entire communication system running through the brain, a new study has found, affecting more regions of the mind than scientists previously thought and shedding new light on how the condition takes hold. Watch Beijing Bicycle Online Beijing Bicycle Full Movie Online more. It's the largest study so far of how white matter (the brain's fatty tissue that enables neurons to communicate) relates to a psychiatric disease, and could help us figure out the mechanisms behind schizophrenia and other mental illnesses. Up until now it was thought that most of the damage done by the condition was in the prefrontal and temporal lobes. Those are the parts of the brain responsible for hearing, defining our personality, and making decisions. But the new study says communications are disrupted all over the brain, like frayed telephone or internet cables – particularly in the corpus callosum, which controls communication between the two hemispheres of the brain. Another badly affected area was the front part of the corona radiata, one of the brain's key structures for processing information.- -- -- -- -- -- -- -- -While we know a lot about the symptoms and consequences of schizophrenia, not much is understood about how it's caused or gets started. Those with the disorder can experience hallucinations and delusions, as well as having trouble thinking and concentrating.

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Though the condition can be managed with drugs, those drugs can have some pretty severe side effects.- -- -- -- -- -- -- -- -Part of the work researchers will be doing in the future is examining exactly how these communication networks in white matter get damaged in the first place – and now they know to look for genes affecting the brain's entire infrastructure, rather than one particular section of internal cabling."Without this study, future research could have been misdirected," says one of the researchers, Neda Jahanshad from USC. We're showing that just studying a single brain region to try to find out what causes schizophrenia is not a good approach. The effect is global.

Focusing on a certain part of the brain where you think that effect will be is not going to give you the whole story.".